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Year/Semester of Study | 4 / Fall Semester | ||||
Level of Course | 1st Cycle Degree Programme | ||||
Type of Course | Optional | ||||
Department | MOLECULAR BIOLOGY AND GENETICS | ||||
Pre-requisities and Co-requisites | None | ||||
Mode of Delivery | Face to Face | ||||
Teaching Period | 14 Weeks | ||||
Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
Name of Lecturer(s) | |||||
Language of Instruction | Turkish | ||||
Work Placement(s) | None | ||||
Objectives of the Course | |||||
The aim of this lecture is to teach basic molecular mechanisms about genesis and development of cancer. |
Learning Outcomes | PO | MME | |
The students who succeeded in this course: | |||
LO-1 | Can explain the DNA repair mechanism. |
PO-3 Identify structure-function relationships in cells and organisms PO-6 Develop an understanding of nature and history of scientific thought PO-8 Develop an awareness of continuous learning in relation with modern technology PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
LO-2 | Can known tumor suppressor genes. |
PO-1 Obtain basic knowledge of Biology PO-2 Develop an understanding of matter and energy in organisms PO-3 Identify structure-function relationships in cells and organisms PO-9 Find out new methods to improve his/her knowledge PO-12 Demonstrate professional and ethical responsibility |
Examination |
LO-3 | Can known the apoptosis. |
PO-2 Develop an understanding of matter and energy in organisms PO-3 Identify structure-function relationships in cells and organisms PO-6 Develop an understanding of nature and history of scientific thought PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics |
Examination |
PO: Programme Outcomes MME:Method of measurement & Evaluation |
Course Contents | ||
Mechanism of cancer, Causes of cancer, DNA repair systems, Tumor suppressor genes, Apoptosis, Onkogenes, Tumor viruses, Molecular therapeutic strategies in cancer | ||
Weekly Course Content | ||
Week | Subject | Learning Activities and Teaching Methods |
1 | Definition and mechanism of Cancer | Explaining |
2 | Carcinogenic agents and cancer stages | Explaining |
3 | Mutations and their role in the cancer process | Explaining |
4 | DNA repair mechanisms and cancer | Explaining |
5 | Tumor suppressor genes | Explaining |
6 | Protooncogenes and oncogenes | Explaining |
7 | Telomerase activity and tumor viruses in cancer cells | Explaining |
8 | mid-term exam | |
9 | Cell cycle and cancer | Explaining |
10 | Apoptosis mechanism and its role in cancer | Explaining |
11 | Epigenetic mechanisms in cancer | Explaining |
12 | Growth factors and receptors | Explaining |
13 | Intracellular signal transduction mechanisms and cancer pathways | Explaining |
14 | Multistep carcinogenesis and metastasis biology | Explaining |
15 | Diagnosis and therapy in Cancer | Explaining |
16 | final exam | |
Recommend Course Book / Supplementary Book/Reading | ||
1 | Molecular Biology of Cancer Mechanisms, Targets and Therapeutics, Lauren Pecorino | |
Required Course instruments and materials | ||
Slides about this lecture subjects |
Assessment Methods | |||
Type of Assessment | Week | Hours | Weight(%) |
mid-term exam | 8 | 2 | 40 |
Other assessment methods | |||
1.Oral Examination | |||
2.Quiz | |||
3.Laboratory exam | |||
4.Presentation | |||
5.Report | |||
6.Workshop | |||
7.Performance Project | |||
8.Term Paper | |||
9.Project | |||
final exam | 16 | 2 | 60 |
Student Work Load | |||
Type of Work | Weekly Hours | Number of Weeks | Work Load |
Weekly Course Hours (Theoretical+Practice) | 2 | 14 | 28 |
Outside Class | |||
a) Reading | 2 | 6 | 12 |
b) Search in internet/Library | 3 | 6 | 18 |
c) Performance Project | 0 | ||
d) Prepare a workshop/Presentation/Report | 2 | 5 | 10 |
e) Term paper/Project | 0 | ||
Oral Examination | 0 | ||
Quiz | 0 | ||
Laboratory exam | 0 | ||
Own study for mid-term exam | 2 | 5 | 10 |
mid-term exam | 1 | 1 | 1 |
Own study for final exam | 2 | 5 | 10 |
final exam | 1 | 1 | 1 |
0 | |||
0 | |||
Total work load; | 90 |