Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

FACULTY OF LETTERS & SCIENCE / MBG 413 - MOLECULAR BIOLOGY AND GENETICS

Code: MBG 413 Course Title: BIOLOGY OF CANCER Theoretical+Practice: 2+0 ECTS: 3
Year/Semester of Study 4 / Fall Semester
Level of Course 1st Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this lecture is to teach basic molecular mechanisms about genesis and development of cancer.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can explain the DNA repair mechanism. PO-3 Identify structure-function relationships in cells and organisms
PO-6 Develop an understanding of nature and history of scientific thought
PO-8 Develop an awareness of continuous learning in relation with modern technology
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-2 Can known tumor suppressor genes. PO-1 Obtain basic knowledge of Biology
PO-2 Develop an understanding of matter and energy in organisms
PO-3 Identify structure-function relationships in cells and organisms
PO-9 Find out new methods to improve his/her knowledge
PO-12 Demonstrate professional and ethical responsibility
Examination
LO-3 Can known the apoptosis. PO-2 Develop an understanding of matter and energy in organisms
PO-3 Identify structure-function relationships in cells and organisms
PO-6 Develop an understanding of nature and history of scientific thought
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Mechanism of cancer, Causes of cancer, DNA repair systems, Tumor suppressor genes, Apoptosis, Onkogenes, Tumor viruses, Molecular therapeutic strategies in cancer
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Definition and mechanism of Cancer Explaining
2 Carcinogenic agents and cancer stages Explaining
3 Mutations and their role in the cancer process Explaining
4 DNA repair mechanisms and cancer Explaining
5 Tumor suppressor genes Explaining
6 Protooncogenes and oncogenes Explaining
7 Telomerase activity and tumor viruses in cancer cells Explaining
8 mid-term exam
9 Cell cycle and cancer Explaining
10 Apoptosis mechanism and its role in cancer Explaining
11 Epigenetic mechanisms in cancer Explaining
12 Growth factors and receptors Explaining
13 Intracellular signal transduction mechanisms and cancer pathways Explaining
14 Multistep carcinogenesis and metastasis biology Explaining
15 Diagnosis and therapy in Cancer Explaining
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Molecular Biology of Cancer Mechanisms, Targets and Therapeutics, Lauren Pecorino
Required Course instruments and materials
Slides about this lecture subjects

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 2 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 2 14 28
Outside Class
       a) Reading 2 6 12
       b) Search in internet/Library 3 6 18
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 2 5 10
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 5 10
mid-term exam 1 1 1
Own study for final exam 2 5 10
final exam 1 1 1
0
0
Total work load; 90