Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

FACULTY OF LETTERS & SCIENCE / MBG 421 - MOLECULAR BIOLOGY AND GENETICS

Code: MBG 421 Course Title: GENOTOXICOLOGY Theoretical+Practice: 2+0 ECTS: 3
Year/Semester of Study 4 / Fall Semester
Level of Course 1st Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
To have knowledge about mutations and mutagens and to explain the mechanisms of cancerogens.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can explain the mutation and mutagens. PO-8 Develop an awareness of continuous learning in relation with modern technology
PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-2 Can known the gene and genom mutations. PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-3 Can explain the techniques used in the detection of mutations. PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Chromosomes, genes and genome mutations, spontaneous and induced mutations, and mechanisms of physical and chemical mutagens, carcinogens .
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Introduction to toxicology Explaining, Question and answer teaching method
2 Classification of poisons Explaining, Question and answer teaching method
3 Important toxic substances found in our environment and industry: Pesticides, Insecticides, fumigants and insect repellants Explaining, Question and answer teaching method
4 Important toxic substances found in our environment and industry: Herbicides, rodenticides, Fungicides, airborn poisons and other sources of toxicity Explaining, Question and answer teaching method
5 Ways of entry of poisons into the body, absorption, distribution and excretion ways Explaining, Question and answer teaching method
6 Metabolism of toxic substances Explaining, Question and answer teaching method
7 Mechanisms of action of toxic substances Explaining, Question and answer teaching method
8 mid-term exam
9 Effects of toxic substances on organs and systems in our body Explaining, Question and answer teaching method
10 Genetic toxicity and changes in cells after exposure to genotoxic substances Explaining, Question and answer teaching method
11 Mutations and factors causing mutations Explaining, Question and answer teaching method
12 Genotoxic Carcinogens Explaining, Question and answer teaching method
13 Teratogens Explaining, Question and answer teaching method
14 Investigation of genotoxicity and risk analysis Explaining, Question and answer teaching method
15 Genotoxicological test methods Explaining, Question and answer teaching method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Molecular Biology of the Cell, Alberts, Garland Science
2 Molecular Cell Biology, Lodish, WH Freeman and Company.
Required Course instruments and materials
Text Book

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 2 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 2 14 28
Outside Class
       a) Reading 2 6 12
       b) Search in internet/Library 3 6 18
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 2 5 10
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 5 10
mid-term exam 1 1 1
Own study for final exam 2 5 10
final exam 1 1 1
0
0
Total work load; 90