Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG527 - MONECULER BIOLOGY AND GENETICS

Code: MBG527 Course Title: ONCOGENESIS AND CARCINOGENESIS Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Fall Semester
Level of Course 2nd Cycle Degree Programme
Type of Course Optional
Department MONECULER BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to gain knowledge and skills about the genetic mechanisms that cause cancer and the multi-step structure of cancer.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can express the basic mechanisms of cancer cell biology. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
LO-2 can knows the basic processes of cancer cell genetics PO-2 Have information about current topics in molecular biology and genetics
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-13 Scientific developments contribute to research and development
LO-3 can discuss the function of oncogen and tumor suppressor genes in carcinogenesis PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
LO-4 can explain the multi-step structure of cancer PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
PO-13 Scientific developments contribute to research and development
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Definition of cancer, multi-step structure of cancer, cancer genetics, definition, classification of oncogenes and their role in cancer, tumor suppressor genes and their effects on cancer formation, invasion, angiogenesis, metastasis
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Definition of cancer Multi-step structure of cancer Explanation Method
2 Cancer genetics Explanation Method
3 Definition and classification of oncogenes Explanation Method
4 The role of oncogenes in cancer Explanation Method
5 Definition and classification of tumor suppressor genes Explanation Method
6 The effects of tumor suppressor genes in cancer formation Explanation Method
7 Oncogenic viruses and their role in tumor formation Explanation Method
8 mid-term exam
9 Genes that control cell cycle Explanation Method
10 Roles of telomeres and telomerase in cancer Explanation Method
11 The role of apoptosis in cancer Explanation Method
12 Transcription factors, growth factors and signal transduction in oncogenesis Explanation Method
13 Extracellular Matrix and Cell Adhesion Molecules Explanation Method
14 invasion, angiogenesis, metastasis Explanation Method
15 Current methods in cancer treatment Explanation Method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Molecular Mechanism of Cancer. Georg F. Weber
Required Course instruments and materials
Course book, course presentations

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 3 7 21
       b) Search in internet/Library 4 8 32
       c) Performance Project 4 7 28
       d) Prepare a workshop/Presentation/Report 3 6 18
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 3 6 18
mid-term exam 1 1 1
Own study for final exam 3 6 18
final exam 2 1 2
0
0
Total work load; 180