Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Fall Semester | ||||
| Level of Course | 2nd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MONECULER BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to teach the basic concepts of oxidative stress and antioxidant systems and to gain knowledge and skills about mechanisms of action. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can explain the formation of free radicals in biological systems. |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems |
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| LO-2 | can describe the diseases caused by oxidative stress. |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form PO-13 Scientific developments contribute to research and development |
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| LO-3 | can explain the importance of antioxidant defense systems. |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it PO-6 Ability to independently carry out an activity that requires expertise in the field PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines |
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| LO-4 | can explain the effects of free radicals on cell components |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
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| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| definition and properties of free radicals, reactive oxygen species (ros) and reactive nitrogen species (rns), oxidation event, phagocytosis and respiratory explosion, effects of free radicals on carbohydrates, lipids, proteins and nucleic acids, antioxidant defense systems, antioxidant species and mechanisms of action, enzymatic antioxidants, non-enzymatic antioxidants, antioxidants and nutrition and health, the role of antioxidants in disease prevention. | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Definition and properties of free radicals | Explanation Method |
| 2 | Reactive oxygen species and reactive nitrogen species | Explanation Method |
| 3 | Oxidation, phagocytosis and respiratory burst | Explanation Method |
| 4 | Effects of free radicals on carbohydrate, lipid and proteins | Explanation Method |
| 5 | Effects of free radicals on nucleic acid and DNA | Explanation Method |
| 6 | Oxidative stress in the development of various diseases | Explanation Method |
| 7 | Antioxidant defense systems and mechanisms of action of antioxidants | Explanation Method |
| 8 | mid-term exam | |
| 9 | Current experimental approaches to the determination of oxidative stress and measurement of oxidative stress | Explanation Method |
| 10 | antioxidants and their mechanisms of action | Explanation Method |
| 11 | Enzymatic antioxidants | Explanation Method |
| 12 | Non-enzymatic antioxidants | Explanation Method |
| 13 | The relationship between nutrition and antioxidant balance | Explanation Method |
| 14 | Current experimental methods for measuring antioxidant activity | Explanation Method |
| 15 | Current experimental methods for measuring antioxidant activity | Explanation Method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Free Radicals in Biology and Medicine, Barry Halliwell and John M. C. Gutteridge | |
| Required Course instruments and materials | ||
| Course book, course presentations | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 1 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 3 | 7 | 21 |
| b) Search in internet/Library | 4 | 8 | 32 |
| c) Performance Project | 4 | 7 | 28 |
| d) Prepare a workshop/Presentation/Report | 3 | 6 | 18 |
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 3 | 6 | 18 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 3 | 6 | 18 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||