Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG518 - MONECULER BIOLOGY AND GENETICS

Code: MBG518 Course Title: OMICS TECHNOLOGIES AND SYSTEM BIOLOGY Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Spring Semester
Level of Course 2nd Cycle Degree Programme
Type of Course Optional
Department MONECULER BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer NAŞİT İĞCİ (nasitigci@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to provide information about data obtaining methods by genome and proteome analysis, bioinformatic analysis of these data, and system biology approach in this context.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can explain basic concepts of system biology. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
PO-13 Scientific developments contribute to research and development
Examination
LO-2 can explain how the data used in system biology is obtained. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
PO-13 Scientific developments contribute to research and development
Examination
LO-3 can give information about the use of bioinformatics in system biology. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
PO-13 Scientific developments contribute to research and development
Examination
LO-4 learn the basic bioinformatics and statistics used in systems biology. PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
PO-13 Scientific developments contribute to research and development
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Genome analyses, transcriptome analyses, proteome analyses, pathway analyses.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Basic concepts of system biology. Lecture, Discussion, Question Answer, Literature Search
2 Structure of genomes. Lecture, Discussion, Question Answer, Literature Search
3 Genomics. Lecture, Discussion, Question Answer, Literature Search
4 Transcriptomics. Lecture, Discussion, Question Answer, Literature Search
5 Bioinformatic analyses used in genomics and transcriptomics. Lecture, Discussion, Question Answer, Literature Search
6 Proteomics. Lecture, Discussion, Question Answer, Literature Search
7 Bioinformatic analyses used in proteomics. Lecture, Discussion, Question Answer, Literature Search
8 mid-term exam
9 Cell signaling. Lecture, Discussion, Question Answer, Literature Search
10 Protein-protein interaction networks. Lecture, Discussion, Question Answer, Literature Search
11 Pathway analyses. Lecture, Discussion, Question Answer, Literature Search
12 Uncovering the cellular mehnasims by pathway analysis. Lecture, Discussion, Question Answer, Literature Search
13 Applications of systems biology. Lecture, Discussion, Question Answer, Literature Search
14 Data mining in systems biology. Lecture, Discussion, Question Answer, Literature Search
15 Databases in systems biology. Lecture, Discussion, Question Answer, Literature Search
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Choi S (Ed.). 2007. Introduction to Systems Biology. Humana Press.
Required Course instruments and materials
Lecture notes, books, related articles, computer

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 4 14 56
       b) Search in internet/Library 4 13 52
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 7 14
mid-term exam 1 1 1
Own study for final exam 2 7 14
final exam 1 1 1
0
0
Total work load; 180