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Year/Semester of Study | 1 / Spring Semester | ||||
Level of Course | 2nd Cycle Degree Programme | ||||
Type of Course | Optional | ||||
Department | MONECULER BIOLOGY AND GENETICS | ||||
Pre-requisities and Co-requisites | None | ||||
Mode of Delivery | Face to Face | ||||
Teaching Period | 14 Weeks | ||||
Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
Name of Lecturer(s) | |||||
Language of Instruction | Turkish | ||||
Work Placement(s) | None | ||||
Objectives of the Course | |||||
The aim of this course is to gain knowledge and skills about the causes and consequences of cell death, the methods of cell death pathways and the current test methods used in the determination of cell death mechanisms. |
Learning Outcomes | PO | MME | |
The students who succeeded in this course: | |||
LO-1 | can explain the species of cell death and the differences between them |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems |
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LO-2 | can discuss the effects of cell death on organism |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics |
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LO-3 | can explain the test methods used to determine cell death pattern |
PO-1 Obtain basic knowledge of Molecular Biology PO-2 Have information about current topics in molecular biology and genetics PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-5 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it PO-6 Ability to independently carry out an activity that requires expertise in the field PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form PO-13 Scientific developments contribute to research and development |
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PO: Programme Outcomes MME:Method of measurement & Evaluation |
Course Contents | ||
Cell death patterns, apoptosis, necrosis, autophagy, entosis, anoikis related concepts and processes, genetic and molecular basis of cell death mechanisms, the importance of cell death patterns for the organism, cell death-related diseases, current methods used to determine the types of cell death | ||
Weekly Course Content | ||
Week | Subject | Learning Activities and Teaching Methods |
1 | Overview of cell death types | Explanation Method |
2 | Programmed cell death: Apoptosis | Explanation Method |
3 | Genetic and molecular mechanisms of apoptosis | Explanation Method |
4 | Role of mitochondria in apoptosis, BCL-2 family and caspases | Explanation Method |
5 | internal pathway in the regulation of apoptosis | Explanation Method |
6 | External pathway in the regulation of apoptosis | Explanation Method |
7 | necrosis | Explanation Method |
8 | mid-term exam | |
9 | Differences between apoptosis and necrosis | Explanation Method |
10 | autophagy | Explanation Method |
11 | Anoikis, paraptosis, entosis | Explanation Method |
12 | factors affecting survival and death decision | Explanation Method |
13 | Diseases associated with cell death | Explanation Method |
14 | Methods used to determine cell death types | Explanation Method |
15 | Methods used to determine cell death types | Explanation Method |
16 | final exam | |
Recommend Course Book / Supplementary Book/Reading | ||
1 | Green D. R. 2011. "MEANS TO AN END Apoptosis and Other Cell Death Mechanisms" | |
Required Course instruments and materials | ||
Course book, course presentations |
Assessment Methods | |||
Type of Assessment | Week | Hours | Weight(%) |
mid-term exam | 8 | 1 | 40 |
Other assessment methods | |||
1.Oral Examination | |||
2.Quiz | |||
3.Laboratory exam | |||
4.Presentation | |||
5.Report | |||
6.Workshop | |||
7.Performance Project | |||
8.Term Paper | |||
9.Project | |||
final exam | 16 | 2 | 60 |
Student Work Load | |||
Type of Work | Weekly Hours | Number of Weeks | Work Load |
Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
Outside Class | |||
a) Reading | 3 | 7 | 21 |
b) Search in internet/Library | 4 | 8 | 32 |
c) Performance Project | 4 | 7 | 28 |
d) Prepare a workshop/Presentation/Report | 3 | 6 | 18 |
e) Term paper/Project | 0 | ||
Oral Examination | 0 | ||
Quiz | 0 | ||
Laboratory exam | 0 | ||
Own study for mid-term exam | 3 | 6 | 18 |
mid-term exam | 1 | 1 | 1 |
Own study for final exam | 3 | 6 | 18 |
final exam | 2 | 1 | 2 |
0 | |||
0 | |||
Total work load; | 180 |