Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG530 - MONECULER BIOLOGY AND GENETICS

Code: MBG530 Course Title: CANCER MOLECULAR BIOLOGY Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Spring Semester
Level of Course 2nd Cycle Degree Programme
Type of Course Optional
Department MONECULER BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to gain basic knowledge and skills related to the process of cancer formation and development.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can explain the mechanisms of cancer formation. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-3 Ability to identify problems in Molecular Biology and genetics, to establish hypotheses for solving problems and to be able to solve hypothesis using various observational and experimental methods
PO-4 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
LO-2 can explain the differences between normal and cancer cells. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
LO-3 can define different types of cancer. PO-1 Obtain basic knowledge of Molecular Biology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
LO-4 can define the genes responsible for cancer development. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-11 Explains the basic functions of scientific processes, critically discusses and solves problems using appropriate statistical and computational methods, chooses contemporary experimental and theoretical approaches that will ultimately lead to the solution of molecular biology and genetic research problems
PO-12 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Fundamentals of cancer process, general characteristics of cancer cell,  cell cycle and apoptosis,   genes responsible for cancer development,  DNA repair mechanisms,   viral carcinogenesis, angiogenic factors, cancer stem cells, hereditary cancer concept, omics approaches to cancer
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Overview of cancer molecular biology Explanation Method
2 Fundamentals of cancer process and genes responsible for cancer development Explanation Method
3 Mutations and chemical carcinogens Explanation Method
4 characteristics of cancer cell Explanation Method
5 Cell cycle and cancer Explanation Method
6 Apoptosis and cancer Explanation Method
7 DNA repair mechanisms and cancer Explanation Method
8 mid-term exam
9 Viral carcinogenesis Explanation Method
10 signaling pathways and cancer Explanation Method
11 Angiogenic factors, Cell-cell interactions in cancer Explanation Method
12 Invasion and metastasis biology Explanation Method
13 Cancer stem cells Explanation Method
14 hereditary cancer concept Explanation Method
15 omics approaches in cancer Explanation Method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Molecular Biology of Cancer Mechanisms, Targets and Therapeutics, Lauren Pecorino
Required Course instruments and materials
Course book, course presentations

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 3 7 21
       b) Search in internet/Library 4 8 32
       c) Performance Project 4 7 28
       d) Prepare a workshop/Presentation/Report 3 6 18
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 3 6 18
mid-term exam 1 1 1
Own study for final exam 3 6 18
final exam 2 1 2
0
0
Total work load; 180