Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Spring Semester | ||||
| Level of Course | 3rd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to provide knowledge and skills to analyze the physical and chemical properties of nanoparticles, their characterization and the effects of nanoparticles on organisms and the environment. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can explain the basic concepts of nanoparticles. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own |
Examination |
| LO-2 | can explain the physicochemical properties and characterization methods of nanoparticles. |
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| LO-3 | can explain the uptake pathways of nanoparticles, their distribution in the cell, and the cellular and molecular stress and death responses to them. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
| LO-4 | can do literature studies on the toxic effects of nanoparticles. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
| LO-5 | can explain the toxic and genotoxic action mechanisms of nanoparticles. |
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-6 | can make an experiment plan to determine the toxicological effects of nanoparticles on the environment. |
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-7 | can explain the nanotoxicological research methods. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
| LO-8 | can make modeling and predictive approaches to the toxic effects of nanoparticles |
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| LO-9 | can make a risk assessment regarding the toxic effects of nanoparticles. |
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Definition of nanoparticles, industrial uses and physicochemical properties, characterization, exposure and uptake of nanoparticles into the cell, their distribution in the cell and the cellular and molecular stress and death responses to them. toxicological effects, nanotoxicology research methods, modeling and predictive approaches, risk assessment and legal limitations | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Definition, industrial uses and physicochemical properties of nanoparticles, | Explanation Method, |
| 2 | Characterization of nanoparticles, | Explanation Method, |
| 3 | Exposure to nanoparticles and their uptake into the cell, | Explanation Method, |
| 4 | Nanoparticle interactions with biological membranes, | Explanation Method, |
| 5 | Distribution of nanoparticles in the cell and cellular and molecular stress and death responses to them | Explanation Method, |
| 6 | Interaction of nanoparticles with intracellular structures, | Explanation Method, |
| 7 | Literature studies examining the effects of nanoparticles on mammalian cells and tissues in vitro and in vivo, | Explanation Method, |
| 8 | mid-term exam | |
| 9 | Effects of nanoparticles on biological systems and intercellular signaling mechanisms, | Explanation Method, |
| 10 | Toxic effects of nanoparticles, | Explanation Method, |
| 11 | Genotoxic action mechanisms of nanoparticles, | Explanation Method, |
| 12 | Toxicological effects of nanoparticles on the environment | Explanation Method, |
| 13 | Nanotoxicology research methods | Explanation Method, |
| 14 | Modeling and predictive approaches | Explanation Method, |
| 15 | Risk assessment and legal limitations | Explanation Method, |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | GMonterio Riviere, N.A. (2007) Nanotoxicology: Characterization, Dosing and Health Effects Informa Health Care Pres | |
| 2 | Yuliang Zhao and Hari Singh Nalwa (2006) Nanotoxicology. Interactions of Nanomaterials with Biological Systems American Scientific Publishers | |
| Required Course instruments and materials | ||
| Course book, course presentations | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 1 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 5 | 8 | 40 |
| b) Search in internet/Library | 5 | 8 | 40 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 5 | 5 | 25 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 5 | 6 | 30 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||