Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Fall Semester | ||||
| Level of Course | 3rd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to provide knowledge and skills to understand the functioning of polymorphic genes by determining the relationship between gene expression and the environment. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can explain the gene-environment relationship. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| LO-2 | can explain the concept of Genetic Polymorphism. |
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-3 | can explain the concept of genetic predisposition and its relationship with genetic diseases. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
| LO-4 | can explain the genetics of behavior. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
| LO-5 | can explain the principles to be considered in personalized drug design. |
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-6 | Can explain experimental evidence of genetic predisposition |
PO-1 Have information about current issues in molecular biology and genetics. |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Gene-environment relationship, genetic polymorphism, the effect of gene and environment on phenotype, the concept of genetic susceptibility and its relationship with genetic diseases, behavioral genetics, genetic predisposition to sex, pharmacogenetics, genetic determinants of alcohol, tobacco and substance abuse, genetic susceptibility to DNA methylating agents, genetic diversity diet and susceptibility to diseases, experimental evidence of genetic predisposition, animal experiments. | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Gene-environment relationship | Explanation Method, |
| 2 | the concept of genetic predisposition and its relationship with genetic diseases, | Explanation Method, |
| 3 | genetic polymorphism, Cytochrome p450 polymorphism, and flavin-containing monooxygenase genes | Explanation Method, |
| 4 | Xenobiotic conjugation polymorphism DNA repair enzyme polymorphism | Explanation Method, |
| 5 | Pharmacogenetics, | Explanation Method, |
| 6 | Genetic susceptibility to environmental toxic agents, | Explanation Method, |
| 7 | Genetic susceptibility to common diseases, | Explanation Method, |
| 8 | mid-term exam | |
| 9 | Sex-linked genetic predisposition, | Explanation Method, |
| 10 | Genetic determinants of alcohol, tobacco and substance abuse | Explanation Method, |
| 11 | Genetic predisposition to DNA methylating agents, | Explanation Method, |
| 12 | Genetic diversity, diet and susceptibility to diseases, | Explanation Method, |
| 13 | Behavioral genetics | Explanation Method, |
| 14 | Experimental evidence of genetic susceptibility, animal experiments, | Explanation Method, |
| 15 | Ethical assessment of genetic susceptibility to diseases | Explanation Method, |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Gene-Environment Interactions: Fundamentals of Ecogenetics, Lucio G. Costa (Editor), David L. Eaton (Editor), Wiley-Blackwell. | |
| 2 | Ecological Genetics: Design, Analysis, and Application ,Andrew Lowe, Stephen Harris, Paul Ashton, Wiley-Blackwell. | |
| Required Course instruments and materials | ||
| Course book, course presentations | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 1 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 5 | 8 | 40 |
| b) Search in internet/Library | 5 | 8 | 40 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 5 | 5 | 25 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 5 | 6 | 30 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||