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Year/Semester of Study | 1 / Spring Semester | ||||
Level of Course | 3rd Cycle Degree Programme | ||||
Type of Course | Optional | ||||
Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
Pre-requisities and Co-requisites | None | ||||
Mode of Delivery | Face to Face | ||||
Teaching Period | 14 Weeks | ||||
Name of Lecturer | MUSA KAR (musa.kar@nevsehir.edu.tr) | ||||
Name of Lecturer(s) | |||||
Language of Instruction | Turkish | ||||
Work Placement(s) | None | ||||
Objectives of the Course | |||||
This course includes basic concepts in immunology, fundamentals of innate and adaptive immunity, mechanisms of action of adaptive immunity, introduction to innate immunity, recognition patterns of innate immunity, complement system, Innate immunity against infections, B and T cell receptors in antigen recognition, antigen-antibody interaction, Antigen-T Cell and MHC relationship, development of lymphocyte antigen receptors, rearrangement of Immunoglobulin genes, rearrangement of T cell receptor genes. |
Learning Outcomes | PO | MME | |
The students who succeeded in this course: | |||
LO-1 | Can explain the cells and organs of the immune system, and the mechanisms of action of innate and adaptive immunity. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
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LO-2 | Can explain how intracellular and extracellular antigens are processed in different pathways and activate different T cells with class I and class II MHC molecules. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
LO-3 | Can explain the developmental processes of T and B cells, and the mechanisms of action of cellular and humoral immunity. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
PO: Programme Outcomes MME:Method of measurement & Evaluation |
Course Contents | ||
Weekly Course Content | ||
Week | Subject | Learning Activities and Teaching Methods |
1 | Innater Immunity | Lecture method |
2 | Major Histocompatibility complex | Lecture method |
3 | Antigen processing and presentation to T lymphocytes | Lecture method |
4 | Antigen receptors and accessory molecules of T and B lymphocytes | Lecture method |
5 | Lymphocyte development and rearrangement and expression of antigen receptor genes | Lecture method |
6 | Activation of T lymphocytes | Lecture method |
7 | B lymphocyte activation and antibody production | Lecture method |
8 | mid-term exam | |
9 | Effector functions of cellular and humoral immunity | Lecture method |
10 | Effector functions of cellular and humoral immunity | Lecture method |
11 | Immune tolerance and autoimmunity | Lecture method |
12 | Immunity to microbes | Lecture method |
13 | Transplantation immunology | Lecture method |
14 | Immunity to Tumors | Lecture method |
15 | General repetition | Lecture method |
16 | final exam | |
Recommend Course Book / Supplementary Book/Reading | ||
1 | 1. Abbas A.K., Lichtman A.H., Pillai S.”Cellular and Molecular Immunology”, Saunders Elsevier, 8th edition (2012). | |
Required Course instruments and materials | ||
Assessment Methods | |||
Type of Assessment | Week | Hours | Weight(%) |
mid-term exam | 8 | 2 | 40 |
Other assessment methods | |||
1.Oral Examination | |||
2.Quiz | |||
3.Laboratory exam | |||
4.Presentation | |||
5.Report | |||
6.Workshop | |||
7.Performance Project | |||
8.Term Paper | |||
9.Project | |||
final exam | 16 | 2 | 60 |
Student Work Load | |||
Type of Work | Weekly Hours | Number of Weeks | Work Load |
Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
Outside Class | |||
a) Reading | 3 | 10 | 30 |
b) Search in internet/Library | 3 | 10 | 30 |
c) Performance Project | 0 | ||
d) Prepare a workshop/Presentation/Report | 3 | 10 | 30 |
e) Term paper/Project | 0 | ||
Oral Examination | 0 | ||
Quiz | 0 | ||
Laboratory exam | 0 | ||
Own study for mid-term exam | 2 | 7 | 14 |
mid-term exam | 1 | 2 | 2 |
Own study for final exam | 3 | 10 | 30 |
final exam | 1 | 2 | 2 |
0 | |||
0 | |||
Total work load; | 180 |