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Year/Semester of Study | 1 / Spring Semester | ||||
Level of Course | 3rd Cycle Degree Programme | ||||
Type of Course | Optional | ||||
Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
Pre-requisities and Co-requisites | None | ||||
Mode of Delivery | Face to Face | ||||
Teaching Period | 14 Weeks | ||||
Name of Lecturer | ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr) | ||||
Name of Lecturer(s) | |||||
Language of Instruction | Turkish | ||||
Work Placement(s) | None | ||||
Objectives of the Course | |||||
The aim of this course is to gain knowledge and skills on the basic concepts of the structure and composition of chromosomes, preparation of chromosome preparation, chromosome staining, banding, karyotype analysis and evaluation of the obtained data. |
Learning Outcomes | PO | MME | |
The students who succeeded in this course: | |||
LO-1 | can explain the general concepts of chromosomes and chromosome structure. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning |
Examination |
LO-2 | can define numerical anomalies in chromosomes. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
LO-3 | can identify structural anomalies in chromosomes |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own |
Examination |
LO-4 | can identify the sex chromosomes |
PO-2 Obtain basic knowledge of Molecular Biology |
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LO-5 | Can explain special chromosome types. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
LO-6 | can define the stages of mitosis. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
LO-7 | can define the stages of meiosis. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
LO-8 | can chromosome preparation can be prepared. |
PO-1 Have information about current issues in molecular biology and genetics. |
Examination |
LO-9 | can explain the chromosome staining techniques |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
LO-10 | can explain the techniques of chromosome banding |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning |
Examination |
LO-11 | can make karyotype analysis and evaluation. |
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
PO: Programme Outcomes MME:Method of measurement & Evaluation |
Course Contents | ||
General concepts about chromosomes and chromosome structure, cell divisions, numerical anomalies in chromosomes, haploplody and polyploidy, somatic chromosome number variations and chimeras, structural anomalies in chromosomes, sex chromosomes and special chromosome types, chromosome preparation preparation, chromosome staining techniques, classification and naming of chromosome bands, Giving information about C, G, R, T, Q and NOR bands and FISH method, karyotype analysis and evaluation. | ||
Weekly Course Content | ||
Week | Subject | Learning Activities and Teaching Methods |
1 | General concepts about chromosomes and chromosome structure, | Explanation Method, |
2 | Numerical anomalies in chromosomes, | Explanation Method, |
3 | Somatic chromosome number variations and chimeras, | Explanation Method, |
4 | Structural anomalies in chromosomes | Explanation Method, |
5 | Structural anomalies in chromosomes | Explanation Method, |
6 | Sex chromosomes | Explanation Method, |
7 | Special chromosome types, | Explanation Method, |
8 | mid-term exam | |
9 | Cell divisions (Mitosis) | Explanation Method, |
10 | Cell divisions (Meiosis) | Explanation Method, |
11 | Chromosome preparation preparation | Explanation Method, |
12 | Chromosome staining techniques | Explanation Method, |
13 | Chromosome banding techniques (information about C, G, R and T banding methods) | Explanation Method, |
14 | Chromosome banding techniques (Q and NOR bands and the FISH method), | Explanation Method, |
15 | karyotype analysis and evaluation. | Explanation Method, |
16 | final exam | |
Recommend Course Book / Supplementary Book/Reading | ||
1 | Emiroğlu, Ü., Bürün B., 2017. "Kromozomlar - Temel Kavramlar ve Mekanizmalar", EGE ÜNİVERSİTESİ YAYINLARI | |
Required Course instruments and materials | ||
Course book, course presentations |
Assessment Methods | |||
Type of Assessment | Week | Hours | Weight(%) |
mid-term exam | 8 | 40 | |
Other assessment methods | |||
1.Oral Examination | |||
2.Quiz | |||
3.Laboratory exam | |||
4.Presentation | |||
5.Report | |||
6.Workshop | |||
7.Performance Project | |||
8.Term Paper | |||
9.Project | |||
final exam | 16 | 60 |
Student Work Load | |||
Type of Work | Weekly Hours | Number of Weeks | Work Load |
Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
Outside Class | |||
a) Reading | 5 | 8 | 40 |
b) Search in internet/Library | 5 | 8 | 40 |
c) Performance Project | 0 | ||
d) Prepare a workshop/Presentation/Report | 0 | ||
e) Term paper/Project | 0 | ||
Oral Examination | 0 | ||
Quiz | 0 | ||
Laboratory exam | 0 | ||
Own study for mid-term exam | 5 | 5 | 25 |
mid-term exam | 1 | 1 | 1 |
Own study for final exam | 5 | 6 | 30 |
final exam | 2 | 1 | 2 |
0 | |||
0 | |||
Total work load; | 180 |