Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

FACULTY OF LETTERS & SCIENCE / MBG 308 - MOLECULAR BIOLOGY AND GENETICS

Code: MBG 308 Course Title: MOLECULAR GENETICS Theoretical+Practice: 3+0 ECTS: 4
Year/Semester of Study 3 / Spring Semester
Level of Course 1st Cycle Degree Programme
Type of Course Compulsory
Department MOLECULAR BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
Aim of the lecture is to explicate genome structure, epigenetic mechanisms, mechanisms of molecular genetic, transcription, translation, post-transcriptional and post-translational regulation mechanisms.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can explain the basic mechanisms of gene expression and protein synthesis, recombination and DNA repair mechanisms. PO-5 Explain transmission of genetic background in organisms and populations
PO-8 Develop an awareness of continuous learning in relation with modern technology
PO-9 Find out new methods to improve his/her knowledge
PO-10 Demonstrate sufficiency in English to follow literature, present technical projects and write articles
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-16 Explain the scientific findings clearly and efficiently both in written and verbal communications.
Examination
LO-2 Can explain the control mechanisms of gene expression. PO-3 Identify structure-function relationships in cells and organisms
PO-5 Explain transmission of genetic background in organisms and populations
PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-3 Can known the post-transcriptional and post-translational modifications. PO-7 Work effectively in multi-disciplinary research teams
PO-8 Develop an awareness of continuous learning in relation with modern technology
PO-9 Find out new methods to improve his/her knowledge
PO-12 Demonstrate professional and ethical responsibility
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Genome structure, Replication epigenetic mechanisms, mechanisms of molecular genetic, transcription, translation, post-transcriptional and post-translational regulation mechanisms
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 History of molecular genetics and the discovery of nucleic acids Explanation
2 Structure of DNA and organization of DNA in chromosomes Explanation
3 The order of genes in the genome and changes in the order of the genes Explanation
4 DNA replication Explanation
5 Structure and types of RNA Explanation
6 Transcription Explanation
7 Post-transcriptional modifications Explanation
8 mid-term exam
9 Translation and proteins Explanation
10 Post-translational modifications Explanation
11 Regulation of gene expression in prokaryotes Explanation
12 Regulation of gene expression in eukaryotes Explanation
13 Molecular genetics of bacteria and viruses Explanation
14 Extrachromosomal DNA in eukaryotes Explanation
15 Mutations and DNA repair mechanisms Explanation
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Leland Hartwell, Leroy Hood, Michael Goldberg, Ann Reynolds and Lee Silver, 2011. Genetics: From Gene to Genomes 4. basım, McGraw-Hill Science/Engineering/Math.
2 Strachan and Read. Human Molecular Genetics 4 Wiley. 2011
3 Güler Temizkan Moleküler Genetik
4 Mehmet Topaktaş Moleküler Genetik
Required Course instruments and materials
textbook, course presentations

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 2 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 2 14 28
       b) Search in internet/Library 1 14 14
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 8 16
mid-term exam 2 1 2
Own study for final exam 2 8 16
final exam 2 1 2
0
0
Total work load; 120