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Year/Semester of Study | 3 / Spring Semester | ||||
Level of Course | 1st Cycle Degree Programme | ||||
Type of Course | Optional | ||||
Department | MOLECULAR BIOLOGY AND GENETICS | ||||
Pre-requisities and Co-requisites | None | ||||
Mode of Delivery | Face to Face | ||||
Teaching Period | 14 Weeks | ||||
Name of Lecturer | ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr) | ||||
Name of Lecturer(s) | |||||
Language of Instruction | Turkish | ||||
Work Placement(s) | None | ||||
Objectives of the Course | |||||
To introduce chromosomal abnormalities at the molecular level, to provide information about chromosomal abnormalities and their causes, to explain molecular mechanisms of mitosis and meiosis in plant and animals. |
Learning Outcomes | PO | MME | |
The students who succeeded in this course: | |||
LO-1 | Can explain the modern techniques in cytogenetics. |
PO-1 Obtain basic knowledge of Biology PO-3 Identify structure-function relationships in cells and organisms PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
LO-2 | Can explain the molecular mechanisms of chromosome abnormalities. |
PO-1 Obtain basic knowledge of Biology PO-9 Find out new methods to improve his/her knowledge PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
LO-3 | Can known the molecular mechanisms of cell cycle, mitosis and meiosis. |
PO-9 Find out new methods to improve his/her knowledge PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics PO-15 Have contributed to scientific advances with research and development abilities |
Examination |
PO: Programme Outcomes MME:Method of measurement & Evaluation |
Course Contents | ||
Nucleus, nucleolus, chromatin, the nuclear proteins, plants and animals in meiosis and mitosis ,molecular organization of the cell cycle, chromosome mutations, telomeres and molecular organization of telomeres. | ||
Weekly Course Content | ||
Week | Subject | Learning Activities and Teaching Methods |
1 | Nucleus and nucleolus, nuclear domains and their molecular organizations. | Explaining, Question and answer teaching method |
2 | Repeated sequences and organization of chromatin , heterochromatin and heterogeneity | Explaining, Question and answer teaching method |
3 | Packaging of chromatin, the control of nucleosome formation by cell cycle control | Explaining, Question and answer teaching method |
4 | Chromosomal variation and chromosome mutations | Explaining, Question and answer teaching method |
5 | The molecular organization of sex chromosomes , genomic organization of chromosome y | Explaining, Question and answer teaching method |
6 | Telomeres and molecular organization, telomeric proteins | Explaining, Question and answer teaching method |
7 | Centromeres, molecular organization of kinetochore, domain organization of centromere and kinetochore | Explaining, Question and answer teaching method |
8 | mid-term exam | |
9 | Molecular mechanisms of centrosome formation, microtubule organizing regions ( MTOC ) and molecular organization of microtubules, molecular motors | Explaining, Question and answer teaching method |
10 | Control points in cell cycles | Explaining, Question and answer teaching method |
11 | The molecular events occurring in plant and animal cytokinesis | Explaining, Question and answer teaching method |
12 | Molecular regulation of meiosis and gene affecting meiosis | Explaining, Question and answer teaching method |
13 | Biochemical events in meiosis prophase , Synaptonemal Complex and molecular organization | Explaining, Question and answer teaching method |
14 | Crossing-over and recombination | Explaining, Question and answer teaching method |
15 | General review | Explaining, Question and answer teaching method |
16 | final exam | |
Recommend Course Book / Supplementary Book/Reading | ||
1 | Plant Cytogenetics: Genome Structure and Chromosome Function (Plant Genetics and Genomics: Crops and Models),Springer, 2011. | |
2 | Molecular Cytogenetics, Ed: Y. Fan; Human Press, Totowa, New Jersey, 2003 | |
Required Course instruments and materials | ||
Text Book |
Assessment Methods | |||
Type of Assessment | Week | Hours | Weight(%) |
mid-term exam | 8 | 1 | 40 |
Other assessment methods | |||
1.Oral Examination | |||
2.Quiz | |||
3.Laboratory exam | |||
4.Presentation | |||
5.Report | |||
6.Workshop | |||
7.Performance Project | |||
8.Term Paper | |||
9.Project | |||
final exam | 16 | 1 | 60 |
Student Work Load | |||
Type of Work | Weekly Hours | Number of Weeks | Work Load |
Weekly Course Hours (Theoretical+Practice) | 2 | 14 | 28 |
Outside Class | |||
a) Reading | 2 | 6 | 12 |
b) Search in internet/Library | 3 | 6 | 18 |
c) Performance Project | 0 | ||
d) Prepare a workshop/Presentation/Report | 2 | 5 | 10 |
e) Term paper/Project | 0 | ||
Oral Examination | 0 | ||
Quiz | 0 | ||
Laboratory exam | 0 | ||
Own study for mid-term exam | 2 | 5 | 10 |
mid-term exam | 1 | 1 | 1 |
Own study for final exam | 2 | 5 | 10 |
final exam | 1 | 1 | 1 |
0 | |||
0 | |||
Total work load; | 90 |