Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

FACULTY OF LETTERS & SCIENCE / MBG 320 - MOLECULAR BIOLOGY AND GENETICS

Code: MBG 320 Course Title: CYTOGENETICS Theoretical+Practice: 2+0 ECTS: 3
Year/Semester of Study 3 / Spring Semester
Level of Course 1st Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
To introduce chromosomal abnormalities at the molecular level, to provide information about chromosomal abnormalities and their causes, to explain molecular mechanisms of mitosis and meiosis in plant and animals.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can explain the modern techniques in cytogenetics. PO-1 Obtain basic knowledge of Biology
PO-3 Identify structure-function relationships in cells and organisms
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-2 Can explain the molecular mechanisms of chromosome abnormalities. PO-1 Obtain basic knowledge of Biology
PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-3 Can known the molecular mechanisms of cell cycle, mitosis and meiosis. PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Nucleus, nucleolus, chromatin, the nuclear proteins, plants and animals in meiosis and mitosis ,molecular organization of the cell cycle, chromosome mutations, telomeres and molecular organization of telomeres.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Nucleus and nucleolus, nuclear domains and their molecular organizations. Explaining, Question and answer teaching method
2 Repeated sequences and organization of chromatin , heterochromatin and heterogeneity Explaining, Question and answer teaching method
3 Packaging of chromatin, the control of nucleosome formation by cell cycle control Explaining, Question and answer teaching method
4 Chromosomal variation and chromosome mutations Explaining, Question and answer teaching method
5 The molecular organization of sex chromosomes , genomic organization of chromosome y Explaining, Question and answer teaching method
6 Telomeres and molecular organization, telomeric proteins Explaining, Question and answer teaching method
7 Centromeres, molecular organization of kinetochore, domain organization of centromere and kinetochore Explaining, Question and answer teaching method
8 mid-term exam
9 Molecular mechanisms of centrosome formation, microtubule organizing regions ( MTOC ) and molecular organization of microtubules, molecular motors Explaining, Question and answer teaching method
10 Control points in cell cycles Explaining, Question and answer teaching method
11 The molecular events occurring in plant and animal cytokinesis Explaining, Question and answer teaching method
12 Molecular regulation of meiosis and gene affecting meiosis Explaining, Question and answer teaching method
13 Biochemical events in meiosis prophase , Synaptonemal Complex and molecular organization Explaining, Question and answer teaching method
14 Crossing-over and recombination Explaining, Question and answer teaching method
15 General review Explaining, Question and answer teaching method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Plant Cytogenetics: Genome Structure and Chromosome Function (Plant Genetics and Genomics: Crops and Models),Springer, 2011.
2 Molecular Cytogenetics, Ed: Y. Fan; Human Press, Totowa, New Jersey, 2003
Required Course instruments and materials
Text Book

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 1 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 2 14 28
Outside Class
       a) Reading 2 6 12
       b) Search in internet/Library 3 6 18
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 2 5 10
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 5 10
mid-term exam 1 1 1
Own study for final exam 2 5 10
final exam 1 1 1
0
0
Total work load; 90