Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

FACULTY OF LETTERS & SCIENCE / MBG 423 - MOLECULAR BIOLOGY AND GENETICS

Code: MBG 423 Course Title: GENOMICS AND PROTEOMICS Theoretical+Practice: 2+0 ECTS: 3
Year/Semester of Study 4 / Fall Semester
Level of Course 1st Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer NAŞİT İĞCİ (nasitigci@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
To teach by comparing the genome structure in various model organisms, to tell concepts and practices of pharmacogenomics and toxicogenomics, to explain protein-protein interactions and protein analysis.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can known the differences between prokaryotic and eukaryotic genome. PO-8 Develop an awareness of continuous learning in relation with modern technology
PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-2 Can known the practices of pharmacogenomics and toxicogenomics. PO-8 Develop an awareness of continuous learning in relation with modern technology
PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
PO-15 Have contributed to scientific advances with research and development abilities
Examination
LO-3 Can explain the protein-protein interactions and protein analysis. PO-6 Develop an understanding of nature and history of scientific thought
PO-9 Find out new methods to improve his/her knowledge
PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics
PO-14 Have knowledge about the main research interests of the molecular biology and genetics
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Comparison of prokaryotic and eukaryotic genomes, toxicogenomics and pharmacogenomics applications, proteomics definition, protein-protein interactions, analysis of proteins.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Comparison of prokaryotic and eukaryotic genome Explaining, Question and answer teaching method
2 Functional genomics Explaining, Question and answer teaching method
3 Genomics applications in human genetic diseases Explaining, Question and answer teaching method
4 Pharmacogenomics and applications Explaining, Question and answer teaching method
5 Toxicogenomics applications Explaining, Question and answer teaching method
6 Nutrigenomics applications Explaining, Question and answer teaching method
7 Definition of proteomics, the relationship between genomics and systems biology Explaining, Question and answer teaching method
8 mid-term exam
9 Visualizations of Protein/peptides in the gel, chip in proteomics applications Explaining, Question and answer teaching method
10 Proteomics in protein modifications, protein-protein interactions Explaining, Question and answer teaching method
11 Peptide/protein analysis by mass spectroscopy Explaining, Question and answer teaching method
12 Evaluation and analysis of mass spectrometry data and proteomics data Explaining, Question and answer teaching method
13 Proteomics applications strategies Explaining, Question and answer teaching method
14 Review Explaining, Question and answer teaching method
15 Review Explaining, Question and answer teaching method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Intoduction to Proteomics: Principles and Applications (Methods of Biochemical Analysis), Nawin C.Mishra, Wiley, 2010.
2 Genomics: Essential Methods, Mike Starkey (Editor), Ramnath Elaswarapu (Editor), Wiley-Blackwell; 1 edition, 2004.
Required Course instruments and materials
Text Book

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 2 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 2 14 28
Outside Class
       a) Reading 2 6 12
       b) Search in internet/Library 3 6 18
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 2 5 10
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 5 10
mid-term exam 1 1 1
Own study for final exam 2 5 10
final exam 1 1 1
0
0
Total work load; 90