Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 4 / Fall Semester | ||||
| Level of Course | 1st Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to gain knowledge and skills about basic concepts and mechanisms related to genome and epigenetics. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can explain the basic concepts of epigenetic mechanisms. |
PO-1 Obtain basic knowledge of Biology PO-3 Identify structure-function relationships in cells and organisms PO-5 Explain transmission of genetic background in organisms and populations PO-6 Develop an understanding of nature and history of scientific thought PO-13 Obtain knowledge about current issues in the field of molecular biology and genetics PO-14 Have knowledge about the main research interests of the molecular biology and genetics |
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| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| DNA methylation, histone modifications, epigenetic mechanisms of gene regulation, genomic imprinting, epigenetic analysis methods, DNA methylation and cancer, diseases associated with abnormal imprinting, DNA methylation and recurrent instability diseases, the role of DNA methylation in human development, embryonic stem cells and differentiation, in other organisms epigenetic approaches | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Definition of epigenetics | Explanation Method |
| 2 | DNA methylation | Explanation Method |
| 3 | histone modifications | Explanation Method |
| 4 | histone modifications | Explanation Method |
| 5 | epigenetic mechanisms in the regulation of gene expression | Explanation Method |
| 6 | epigenetic mechanisms in the regulation of gene expression | Explanation Method |
| 7 | genomic imprinting | Explanation Method |
| 8 | mid-term exam | |
| 9 | epigenetic analysis methods | Explanation Method |
| 10 | epigenetic analysis methods | Explanation Method |
| 11 | epigenetic-related diseases | Explanation Method |
| 12 | epigenetics in cancer formation and development | Explanation Method |
| 13 | epigenetic and developmental biology | Explanation Method |
| 14 | Epigenetics in stem cell biology | Explanation Method |
| 15 | Epigenetic regulation mechanisms in other organisms | Explanation Method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Chadwick, B. P. 2015 “Epigenetics Current Research and Emerging Trends “ | |
| Required Course instruments and materials | ||
| Textbooks | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 1 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 1 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 2 | 14 | 28 |
| Outside Class | |||
| a) Reading | 2 | 6 | 12 |
| b) Search in internet/Library | 3 | 6 | 18 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 2 | 5 | 10 |
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 2 | 5 | 10 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 2 | 5 | 10 |
| final exam | 1 | 1 | 1 |
| 0 | |||
| 0 | |||
| Total work load; | 90 | ||