Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG519 - MONECULER BIOLOGY AND GENETICS

Code: MBG519 Course Title: PROTEIN BIOCHEMISTRY Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Fall Semester
Level of Course 2nd Cycle Degree Programme
Type of Course Optional
Department MONECULER BIOLOGY AND GENETICS
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer NAŞİT İĞCİ (nasitigci@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to gain knowledge about basic structure and properties of proteins.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can explain chemical structures and physicochemical properties of amino acids. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-13 Scientific developments contribute to research and development
Examination
LO-2 can explain chemical structures and physicochemical properties of proteins. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-13 Scientific developments contribute to research and development
Examination
LO-3 can explain the basic concepts of protein metabolism. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-13 Scientific developments contribute to research and development
Examination
LO-4 can explain post-translational modifications of proteins. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-13 Scientific developments contribute to research and development
Examination
LO-5 can explain the basic concepts of protein-ligand interactions. PO-1 Obtain basic knowledge of Molecular Biology
PO-2 Have information about current topics in molecular biology and genetics
PO-6 Ability to independently carry out an activity that requires expertise in the field
PO-8 Ability to participate in interdisciplinary studies in the fields of education, industry, agriculture, health, environment, energy and biotechnology
PO-9 Recognizes and explains the molecular biology and genetics of the problems of other disciplines
PO-10 Read and critically discuss the world-wide literature on molecular biology and molecular genetics
PO-13 Scientific developments contribute to research and development
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Chemical structures and physicochemical properties of amino acids, chemical structures and physicochemical properties of proteins, three-dimensional structures of proteins, protein-ligand interactions, protein metabolism, post-translational modifications.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 The history of protein researches and the milestones of protein research. Lecture, Discussion, Question Answer, Literature Search
2 The importance and functions of proteins in the cell. Lecture, Discussion, Question Answer, Literature Search
3 Chemical structure of amino acids. Lecture, Discussion, Question Answer, Literature Search
4 Reactions and detection of amino acids. Lecture, Discussion, Question Answer, Literature Search
5 Physicochemical properties of amino acids. Lecture, Discussion, Question Answer, Literature Search
6 Polypeptide biosynthesis. Lecture, Discussion, Question Answer, Literature Search
7 Natural and synthetic peptides. Lecture, Discussion, Question Answer, Literature Search
8 mid-term exam
9 Chemical structure of proteins. Lecture, Discussion, Question Answer, Literature Search
10 Physicochemical properties of proteins. Lecture, Discussion, Question Answer, Literature Search
11 Three dimensional structure of proteins and protein-ligand interactions. Lecture, Discussion, Question Answer, Literature Search
12 Protein solubility, denaturation and renaturation. Lecture, Discussion, Question Answer, Literature Search
13 Classification of proteins according to their structure and function. Lecture, Discussion, Question Answer, Literature Search
14 Enzymes. Lecture, Discussion, Question Answer, Literature Search
15 Protein analyses. Lecture, Discussion, Question Answer, Literature Search
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Walsh G. 2005. Proteins: Biochemistry and Biotechnology. John Wiley & Sons.
Required Course instruments and materials
Lecture notes, books, related articles, computer

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 1 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 4 14 56
       b) Search in internet/Library 4 13 52
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 2 7 14
mid-term exam 1 1 1
Own study for final exam 2 7 14
final exam 1 1 1
0
0
Total work load; 180