Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Spring Semester | ||||
| Level of Course | 2nd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MONECULER BIOLOGY AND GENETICS | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | MUSA KAR (musa.kar@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| To lead students to gain below outcomes; 1: will have information about the tissues and cells of the immune system, 2: know mechanisms of the innate and adaptive immunity, 3: have knowledge about integration of the cellular and humoral immunities against pathogens that invade our organisms, molecular bases of the antigen processing and antigen presentation to the immune system. 4: This basic knowledge will allow students to better understand topics such as diseases of the immune system, transplantation, allergy and tumor immunology. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | Define cells and tissues of the immune system and effector mechanisms of innate and adaptive immuniies |
PO- |
Examination |
| LO-2 | Distinguish differential processing of intracellular and extracellular antigens and their activation of distinct subsets of T cells by MHC class I and MHC class II molecules. |
PO- |
Examination |
| LO-3 | Explain development of T and B cells and the mechanisms of cellular and humoral immunities. |
PO- |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Definitions of immunology, definitions of acquired and adaptive immunity and differential differences, immune system cell types, antibody-antigen functions, processing of antigens and submission to defense cells, autoimmune disorders | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Basic concepts in immunology. The bases of innate and adaptive immunity. | Discussion Method, Narrative Method |
| 2 | Cells and tissues of the immune system | Discussion Method, Narrative Method |
| 3 | Circulation of cells of the immune system and theri migration into tissues | Discussion Method, Narrative Method |
| 4 | Innate immunity: cellular abd soluble sensors and effector molecules. Inflammation and anti-viral response. Complement system | Discussion Method, Narrative Method |
| 5 | Antigens and antibodies. Structure-function relationship of antibodies. The chemistry of antigen-antibody binding. | Discussion Method, Narrative Method |
| 6 | Antigen processing in MHC Class I and II pathways. Functions of MHC Complex. Prsentation of antigens to T cells. | Discussion Method, Narrative Method |
| 7 | Signaling through immune system and cytokine receptors | Discussion Method, Narrative Method |
| 8 | mid-term exam | |
| 9 | Development of B and T lymphocytes. Mechanisms of rearrangement of antigen receptors. | Discussion Method, Narrative Method |
| 10 | Activation of T cells. Activating signals and functional responses. | Discussion Method, Narrative Method |
| 11 | Differentiation and functions of CD4 and CD8 T cells. Properties of effector T cells. T Cell-dependent cytotoxicity. | Discussion Method, Narrative Method |
| 12 | Activation of B cells and antibody production. | Discussion Method, Narrative Method |
| 13 | Humaral immune responses. Functions of antibody isotypes | Discussion Method, Narrative Method |
| 14 | Structure of mucosal immune system.and mucosal immune responses against pathogens. | Discussion Method, Narrative Method |
| 15 | General Assessment | Discussion Method, Narrative Method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Abul K. Abbas, Andrew H. Lichtman, & Shiv Pillai. Cellular and Molecular Immunology, 9. baskı, Elsevier (2018) ISBN: 978-0-323-52324- | |
| Required Course instruments and materials | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 3 | 14 | 42 |
| b) Search in internet/Library | 3 | 10 | 30 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 2 | 1 | 2 |
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 3 | 10 | 30 |
| mid-term exam | 2 | 1 | 2 |
| Own study for final exam | 3 | 10 | 30 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||