Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Fall Semester | ||||
| Level of Course | 3rd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to gain knowledge and skills to understand the genome structure and organization in animals at the chromosome and gene level and to learn advanced cytogenetic and molecular techniques used in genome research. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can explain the definition of cytogenetics and the purpose of chromosome studies. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own |
Examination |
| LO-2 | can explain the structure and types of chromosomes. |
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| LO-3 | can explain the methods of obtaining chromosomes from animals in vivo and in vitro. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
| LO-4 | can explain the techniques of chromosome staining and banding. |
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-5 | can explain the methods of making permanent preparations |
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-6 | can determine and evaluate karyotype and idiotype, centromere index of chromosomes, arm ratio and relative lengths |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| LO-7 | can use computer programs in making karyotype and idiogram. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| LO-8 | can explain the production of chromosomal studies with in situ hybridization techniques. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| LO-9 | can explain working methods with germ cells. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| LO-10 | can explain the use of flow cytometry in mammalian chromosome analysis and arrangement. |
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-11 | Can define numerical and structural chromosomal anomalies. |
PO-1 Have information about current issues in molecular biology and genetics. |
Examination |
| LO-12 | Can explain the basic information about the genetic counseling field. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Definition of cytogenetics and purpose of chromosome studies, structure and types of chromosomes, methods of obtaining chromosomes from animals in vivo and in vitro, production techniques of chromosome preparations, chromosome staining and banding techniques, permanent preparation methods, karyotype and idiotype, centromere index of chromosomes, arm ratio and Determination and evaluation of relative lengths, programs used in making karyotype and idiogram, In situ hybridization techniques in determining chromosomes, methods of karyotyping with germ cells, flow cytometry in chromosome analysis and arrangement, genetic counseling. | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Definition of cytogenetics and purpose of chromosome studies | Explanation Method |
| 2 | Structure and types of chromosomes | Explanation Method |
| 3 | Numerical and structural chromosomal abnormalities, | Explanation Method |
| 4 | Methods of obtaining in vivo and in vitro chromosomes from animals | Explanation Method |
| 5 | Production techniques of chromosome preparations in animals, | Explanation Method |
| 6 | Methods of working with germ cells, | Explanation Method |
| 7 | Chromosome staining and banding techniques, | Explanation Method |
| 8 | mid-term exam | |
| 9 | Chromosome staining and banding techniques, | Explanation Method |
| 10 | Permanent preparation methods, | Explanation Method |
| 11 | Determination and evaluation of karyotype and idiotype, centromere index of chromosomes, arm ratio and relative lengths | Explanation Method |
| 12 | Programs used in making karyotype and idiogram | Explanation Method |
| 13 | Flow cytometry in its application in mammalian chromosome analysis and arrangement | Explanation Method |
| 14 | In situ hybridization techniques, | Explanation Method |
| 15 | Genetic counseling. | Explanation Method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Sitogenetik Prof. Dr. M. TOPAKTAŞ, Prof. Dr. E. RENCÜZOĞULLARI, | |
| 2 | Popescu, P., Hayes, H., Dutrillaux, B., "Techniques in Animal Cytogenetics", Springer-Verlag Berlin Heidelberg 2000 | |
| Required Course instruments and materials | ||
| Course book and presentations | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 1 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 5 | 8 | 40 |
| b) Search in internet/Library | 5 | 8 | 40 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 5 | 6 | 30 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 5 | 5 | 25 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||