Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG607 - MOLECULAR BIOLOGY AND GENETICS (PHD)

Code: MBG607 Course Title: ADVANCED MOLECULAR AND CELL BIOLOGY Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Fall Semester
Level of Course 3rd Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS (PHD)
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to provide basic information about cell structure at the molecular level and to gain knowledge and skills for research on these subjects.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 Can explain the basic concepts related to the structure of prokaryotic and eukaryotic molecular cells. PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
Examination
LO-2 Can explain the molecular structure of the cell membrane. PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
Examination
LO-3 Can explain the principles of substance transport across the membrane. PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-4 Can explain cell surface molecules and extracellular matrix attachment sites. PO-1 Have information about current topics in molecular biology and genetics
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Scientific developments contribute to research and development
Examination
LO-5 Can explain the mechanisms of cellular communication and second messenger systems. PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
Examination
LO-6 Can explain the molecular structure of the cytoskeleton and cell movement. PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-7 Can explain the molecular structure and functions of cell organelles in detail. PO-2 Obtain basic knowledge of Molecular Biology
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
Examination
LO-8 Can explain the structure and organization of the nucleus. PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
Examination
LO-9 Can explain the replication process at the molecular level. PO-1 Have information about current topics in molecular biology and genetics
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Scientific developments contribute to research and development
Examination
LO-10 Can explain transcriptional and post-transcriptional modifications. PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
Examination
LO-11 Can explain translational mechanisms and post-translational modifications. PO-1 Have information about current topics in molecular biology and genetics
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Scientific developments contribute to research and development
Examination
LO-12 Can explain the structure and functions of proteins by giving examples. PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
Examination
LO-13 Can make detailed explanations about cell divisions. PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
The molecular structure of prokaryotic and eukaryotic cells, the molecular structure of the cell membrane and the principles of substance transport across the membrane, the cell surface molecules and the extracellular matrix, the junctional sites, the mechanisms of cellular communication, the second messenger systems, the cytoskeleton and cell movement, the molecular structure and functions of cell organelles, the structure of the nucleus. and its organization, replication, transcription and translation mechanisms, proteins, cell divisions
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Prokaryotic and eukaryotic molecular cells structure, Explanation Method
2 The molecular structure of the cell membrane and the principles of substance transport in cell membranes, Explanation Method
3 Cell surface molecules and extracellular matrix, attachment sites, Explanation Method
4 Mechanisms of cellular communication: Receptors on the cell membrane and signal transmission, Explanation Method
5 Transmission of the signal in the cytoplasm, Second messenger systems Explanation Method
6 Cytoskeleton and cell movement, filaments, microtubules, Explanation Method
7 Intracellular vesicular traffic: Ribosomes, endoplasmic reticulum, Explanation Method
8 mid-term exam
9 Golgi apparatus, lysosomes, peroxisomes Explanation Method
10 Intracellular energy conversion: Mitochondria and chloroplasts Explanation Method
11 Structure and organization of the nucleus, mechanisms of replication and transcription, Explanation Method
12 Transcription and post-transcriptional modifications Explanation Method
13 Translational and post-translational modifications Explanation Method
14 Proteins Explanation Method
15 Cell divisions, Explanation Method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Alberts B., Johnson A., Lewis J., Raff M., Roberts K. and Walter P., 2008. “Molecular Biology of the Cell, fourth edition”
Required Course instruments and materials
Course book and presentations

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 5 8 40
       b) Search in internet/Library 5 8 40
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 5 5 25
mid-term exam 1 1 1
Own study for final exam 5 6 30
final exam 2 1 2
0
0
Total work load; 180