Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Fall Semester | ||||
| Level of Course | 3rd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | ZÜBEYDE KUMBIÇAK (zkumbicak@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to gain knowledge and skills about the factors and mechanisms that function in the regulation of gene expression in living things at different organizational levels. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can define the concept of gene. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
| LO-2 | can explain the structure and scope of genes. |
PO-1 Have information about current issues in molecular biology and genetics. PO-2 Obtain basic knowledge of Molecular Biology |
Examination |
| LO-3 | can explain the principles of transcriptional regulation in prokaryotes and eukaryotes. |
PO-2 Obtain basic knowledge of Molecular Biology PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-4 | can explain the gene rearrangements required for the initiation of transcription and in the subsequent steps. |
PO-1 Have information about current issues in molecular biology and genetics. PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| LO-5 | can explain alternative pathways in the control of gene expression. |
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-6 | can explain the regulation steps of post-transcriptional gene expression in prokaryotic and eukaryotic systems. |
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-7 | can explain the molecular mechanism of gene translation. |
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| LO-8 | can explain the regulation steps of post-translational gene expression in prokaryotic and eukaryotic systems. |
PO-1 Have information about current issues in molecular biology and genetics. PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-9 | can explain the role of epigenetic factors in gene expression and regulation. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| LO-10 | can explain the relationship between cell division, development and differentiation and regulation of gene expression. |
PO-1 Have information about current topics in molecular biology and genetics PO-2 Obtain basic knowledge of Molecular Biology PO-3 Scientific developments contribute to research and development |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Gene concept, structure of genes, principles of transcriptional regulation in prokaryotes and eukaryotes, alternative pathways in the control of gene expression, regulation steps of post-transcriptional gene expression in prokaryotic and eukaryotic systems, molecular mechanism of gene translation, regulation steps of post-translational gene expression in prokaryotic and eukaryotic systems, epigenetic factors its role in gene expression, the relationship between cell division, development and differentiation, and regulation of gene expression | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Genes, structure and scope of genes | Explanation Method |
| 2 | Principles of transcriptional regulation in prokaryotes | Explanation Method |
| 3 | Regulation of initiation of transcription | Explanation Method |
| 4 | Gene regulation in steps after transcription initiation | Explanation Method |
| 5 | Alternative pathways in the control of gene expression | Explanation Method |
| 6 | Regulation of post-transcriptional gene expression in prokaryotic systems | Explanation Method |
| 7 | Principles of transcriptional regulation in eukaryotes | Explanation Method |
| 8 | mid-term exam | |
| 9 | Conserved mechanisms of transcriptional regulation in eukaryotes | Explanation Method |
| 10 | Regulation of post-transcriptional gene expression in eukaryotic systems | Explanation Method |
| 11 | Molecular mechanism of gene translation | Explanation Method |
| 12 | Regulation of post-translational gene expression in prokaryotic systems | Explanation Method |
| 13 | Regulation of post-translational gene expression in eukaryotic systems | Explanation Method |
| 14 | Epigenetic factors in the regulation of gene expression | Explanation Method |
| 15 | Relationship between cell division, development and differentiation and regulation of gene expression | Explanation Method |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | -Regulation of Gene Expression, 2008, by Gary H. Perdew and Jack P. Vanden Heuvel | |
| Required Course instruments and materials | ||
| Course book and presentations | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 1 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 5 | 8 | 40 |
| b) Search in internet/Library | 5 | 8 | 40 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 5 | 5 | 25 |
| mid-term exam | 1 | 1 | 1 |
| Own study for final exam | 5 | 6 | 30 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 180 | ||