Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG626 - MOLECULAR BIOLOGY AND GENETICS (PHD)

Code: MBG626 Course Title: ADVANCED POPULATION GENETICS Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Spring Semester
Level of Course 3rd Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS (PHD)
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to provide knowledge and skills the basic concepts of population genetics, the factors affecting the genetic structure of the population, and to calculate the changes in gene frequencies of populations.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can explain the basic concepts of genetics and population genetics. PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
Examination
LO-2 can explain growth curves and population dynamics of populations PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-3 can explain the Hardy-Weinberg principles. PO-1 Have information about current topics in molecular biology and genetics
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Scientific developments contribute to research and development
PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
Examination
LO-4 can explain the factors that change gene frequency. PO-1 Have information about current topics in molecular biology and genetics
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Scientific developments contribute to research and development
PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
Examination
LO-5 can explain the formation of new alleles and the relationship between selection and mutation equilibrium. PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-6 can explain polygenic inheritance in terms of population genetics. PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-7 can plan studies on population genetics. PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Basic concepts in genetics and population genetics, population growth curves, population dynamics, Hardy-Weinberg principle, gene and genotype frequencies, Frequency for multiple alleles and X-linked traits, Factors that change gene frequency; mutation and its effects, migration; gene flow and genetic drift, selection, mutation, selection of heterozygotes, small populations and gene frequency variation, inbreeding and gene frequency variation, effective population size, inbreeding parentage coefficient, random mating in populations, genetic variation, polygenic inheritance, quantitative genetics and heritability.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Basic concepts in genetics and population genetics, Explanation Method
2 Growth curves of populations, population dynamics, Explanation Method
3 Hardy-Weinberg principle, gene and genotype frequencies, Explanation Method
4 Frequency for multiple alleles and X-linked traits, Explanation Method
5 Factors that change gene frequency; mutation and its effects, migration; gene flow and genetic drift, Explanation Method
6 Selection; gamete selection, zygote selection, recessive and dominant genes versus selection, Explanation Method
7 Change of gene frequencies, natural selection, mutation, Explanation Method
8 mid-term exam
9 The formation of new alleles and the balance of selection and mutation, Explanation Method
10 Selection of heterozygotes, small populations and gene frequency variation, Explanation Method
11 Inbreeding and gene frequency variation, effective population size. Explanation Method
12 Inbreeding parenting coefficient, Explanation Method
13 Random mating, genetic variation, Explanation Method
14 polygenic inheritance, Explanation Method
15 Quantitative genetics and heritability. Explanation Method
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Population Genetics, 2009. Matthew B. Hamilton. Wiley-Blackwell, UK
2 Principles of Population Genetics Hartl, D.L & A.G Clark, 2007
Required Course instruments and materials
Course book, course presentations

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 5 8 40
       b) Search in internet/Library 5 8 40
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 5 5 25
mid-term exam 1 1 1
Own study for final exam 5 6 30
final exam 2 1 2
0
0
Total work load; 180