Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG617 - MOLECULAR BIOLOGY AND GENETICS (PHD)

Code: MBG617 Course Title: ADVANCED EUKARYOTIC MOLECULAR GENETICS Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Fall Semester
Level of Course 3rd Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS (PHD)
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer ÜMİT KUMBIÇAK (umitkumbicak@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to gain knowledge and skills about genome structures, functions and operations and the use of genome databases.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can explain the genome structures of eukaryotes. PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
Examination
LO-2 can explain replication and replication control mechanisms. PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-3 can explain RNA structure, types, transcription process and RNA processing steps. PO-1 Have information about current topics in molecular biology and genetics
PO-2 Obtain basic knowledge of Molecular Biology
PO-3 Scientific developments contribute to research and development
PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form
Examination
LO-4 can explain with examples the mechanisms of translation initiation, translational control and gene expression control in eukaryotes. PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-5 can explain organelle genome structures and gene expression. PO-1 Have information about current issues in molecular biology and genetics.
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
Examination
LO-6 Can perform genome analysis by using databases. PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-7 Explain the control patterns of gene expression in cell signal transduction and embryonic development. PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-8 Explain the importance of controlling gene expression in cancer and human genetic diseases. PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Genome structures, replication and replication control mechanisms in eukaryotes, RNA structure, types, transcription and transcription control mechanisms, RNA processing, translation initiation and translational control in eukaryotes, control mechanisms of gene expression, organelle genome structures and gene expression, using databases and genome analysis methods, omic studies
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Genome structures in eukaryotes, Explanation Method,
2 Replication and replication control mechanisms in eukaryotes, Explanation Method,
3 RNA structure, types, Explanation Method,
4 Transcription and control mechanisms of transcription, Explanation Method,
5 RNA processing, Explanation Method,
6 Translation initiation and translational control in eukaryotes, Explanation Method,
7 control mechanisms of gene expression in eukaryotes, Explanation Method,
8 mid-term exam
9 Mitochondrial genes and comparisons Explanation Method,
10 Chloroplast genes and comparisons Explanation Method,
11 Control of gene expression in cell signal transduction and embryonic development, Explanation Method,
12 Control of gene expression in cancer and human genetic diseases, Explanation Method,
13 Eukaryotic proteins and their functions, Explanation Method,
14 Comparisons of eukaryotic genomes, Using databases, Explanation Method,
15 Genome analysis methods, omic studies, Explanation Method,
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Genetik Kavramlar. Palme Yayınevi.
2 Eliot, Ladomery, Molecular Biology of RNA, Oxford Publications,
Required Course instruments and materials
Course book, course presentations

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 1 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 2 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 5 8 40
       b) Search in internet/Library 5 8 40
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 5 5 25
mid-term exam 1 1 1
Own study for final exam 5 6 30
final exam 2 1 2
0
0
Total work load; 180