Nevşehir Hacı Bektaş Veli University Course Catalogue
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| Year/Semester of Study | 1 / Spring Semester | ||||
| Level of Course | 3rd Cycle Degree Programme | ||||
| Type of Course | Optional | ||||
| Department | MOLECULAR BIOLOGY AND GENETICS (PHD) | ||||
| Pre-requisities and Co-requisites | None | ||||
| Mode of Delivery | Face to Face | ||||
| Teaching Period | 14 Weeks | ||||
| Name of Lecturer | NAŞİT İĞCİ (nasitigci@nevsehir.edu.tr) | ||||
| Name of Lecturer(s) | |||||
| Language of Instruction | Turkish | ||||
| Work Placement(s) | None | ||||
| Objectives of the Course | |||||
| The aim of this course is to provide information about the processes related to drug discovery and development, the studies carried out in these processes and the regulations related to clinical research. | |||||
| Learning Outcomes | PO | MME | |
| The students who succeeded in this course: | |||
| LO-1 | can give information about drug discovery. |
PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
| LO-2 | can explain approaches used in the drug discovery. |
PO-1 Have information about current issues in molecular biology and genetics. PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it |
Examination |
| LO-3 | can obtain information about the discovery process of a drug using library and internet resources. |
PO-4 To be able to transfer current developments and own studies in the field with quantitative and qualitative data to the groups in the field and outside the field in a systematic manner in written, oral and visual form |
Examination |
| LO-4 | can give information about ethics in drug research. |
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning PO-5 Being ethical and responsible individuals who are sensitive to social and universal values in the field of Molecular Biology and genetics, who look after the priority areas of the country, research and produce and contribute to these issues |
Examination |
| PO: Programme Outcomes MME:Method of measurement & Evaluation |
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| Course Contents | ||
| Types of drugs, studies and methods used for drug discovery, natural resources used for drug discovery, use of bioinformatics and artificial intelligence in drug discovery, preclinical research in drug discovery, drug patenting, clinical phase research, drug formulations, vaccine development, drug development regulations. | ||
| Weekly Course Content | ||
| Week | Subject | Learning Activities and Teaching Methods |
| 1 | Introduction to drug research: Pharmacology | Lecture, Discussion, Question Answer, Literature Search |
| 2 | Drug types I: small molecules | Lecture, Discussion, Question Answer, Literature Search |
| 3 | Drug types II: peptides | Lecture, Discussion, Question Answer, Literature Search |
| 4 | Drug types III: antibodies | Lecture, Discussion, Question Answer, Literature Search |
| 5 | Vaccine development | Lecture, Discussion, Question Answer, Literature Search |
| 6 | Sources for drug discovery | Lecture, Discussion, Question Answer, Literature Search |
| 7 | Approaches and methods used in drug discovery | Lecture, Discussion, Question Answer, Literature Search |
| 8 | mid-term exam | |
| 9 | Use of artificial intelligence in drug development | Lecture, Discussion, Question Answer, Literature Search, Case Study |
| 10 | Target selection for drug discovery | Lecture, Discussion, Question Answer, Literature Search |
| 11 | Formulation and optimization of a drug candidate | Lecture, Discussion, Question Answer, Literature Search |
| 12 | Pre-clinical studies in drug discovery | Lecture, Discussion, Question Answer, Literature Search |
| 13 | Clinical phase studies in drug discovery | Lecture, Discussion, Question Answer, Literature Search |
| 14 | Patenting and regulations | Lecture, Discussion, Question Answer, Literature Search |
| 15 | Ethics in drug research | Lecture, Discussion, Question Answer, Literature Search, Case Study |
| 16 | final exam | |
| Recommend Course Book / Supplementary Book/Reading | ||
| 1 | Hill RG, Richards D (Eds.). (2021). Drug Discovery and Development. Elsevier. | |
| Required Course instruments and materials | ||
| Lecture notes, books, related articles, computer | ||
| Assessment Methods | |||
| Type of Assessment | Week | Hours | Weight(%) |
| mid-term exam | 8 | 2 | 40 |
| Other assessment methods | |||
| 1.Oral Examination | |||
| 2.Quiz | |||
| 3.Laboratory exam | |||
| 4.Presentation | |||
| 5.Report | |||
| 6.Workshop | |||
| 7.Performance Project | |||
| 8.Term Paper | |||
| 9.Project | |||
| final exam | 16 | 2 | 60 |
| Student Work Load | |||
| Type of Work | Weekly Hours | Number of Weeks | Work Load |
| Weekly Course Hours (Theoretical+Practice) | 3 | 14 | 42 |
| Outside Class | |||
| a) Reading | 3 | 14 | 42 |
| b) Search in internet/Library | 3 | 14 | 42 |
| c) Performance Project | 0 | ||
| d) Prepare a workshop/Presentation/Report | 0 | ||
| e) Term paper/Project | 0 | ||
| Oral Examination | 0 | ||
| Quiz | 0 | ||
| Laboratory exam | 0 | ||
| Own study for mid-term exam | 3 | 7 | 21 |
| mid-term exam | 2 | 1 | 2 |
| Own study for final exam | 3 | 7 | 21 |
| final exam | 2 | 1 | 2 |
| 0 | |||
| 0 | |||
| Total work load; | 172 | ||