Nevşehir Hacı Bektaş Veli University Course Catalogue

Information Of Programmes

INSTITUTE OF SCIENCE / MBG620 - MOLECULAR BIOLOGY AND GENETICS (PHD)

Code: MBG620 Course Title: PROTEINS AS A BIOTECHNOLOGICAL PRODUCT Theoretical+Practice: 3+0 ECTS: 6
Year/Semester of Study 1 / Spring Semester
Level of Course 3rd Cycle Degree Programme
Type of Course Optional
Department MOLECULAR BIOLOGY AND GENETICS (PHD)
Pre-requisities and Co-requisites None
Mode of Delivery Face to Face
Teaching Period 14 Weeks
Name of Lecturer NAŞİT İĞCİ (nasitigci@nevsehir.edu.tr)
Name of Lecturer(s)
Language of Instruction Turkish
Work Placement(s) None
Objectives of the Course
The aim of this course is to give information about protein biochemistry, protein purification methods, protein engineering, antibody production and to give examples of how proteins can be used as biotechnological products.

Learning Outcomes PO MME
The students who succeeded in this course:
LO-1 can explain the basic concepts of biotechnology. PO-1 Have information about current issues in molecular biology and genetics.
PO-2 Obtain basic knowledge of Molecular Biology
Examination
LO-2 can explain how proteins are used as biotechnological products. PO-1 Have information about current issues in molecular biology and genetics.
Examination
LO-3 can conduct research on the commercial value of biotechnological products. PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
PO-4 Evaluate the knowledge and skills in a critical way in every activity regarding the field, thereby guiding their learning
PO-6 Ability to design a research project in the field of molecular biology and genetics and to evaluate and present the results related to it
Examination
LO-4 can explain how proteins are produced to be used as biotechnological products. PO-1 Have information about current issues in molecular biology and genetics.
PO-3 Make use of the knowledge they have in order to find a solution to problems by analyzing, comparing and questioning them and can carry out original research in the related field on their own
Examination
PO: Programme Outcomes
MME:Method of measurement & Evaluation

Course Contents
Protein biochemistry, protein separation and purification methods, protein engineering, antibodies as a biotechnological product, antibody production and engineering, large-scale production of proteins, enzymes as a biotechnological product, enzyme immobilization, recombinant DNA technology.
Weekly Course Content
Week Subject Learning Activities and Teaching Methods
1 Definition and history of biotechnology. Lecture notes, books, related articles, computer
2 Protein biochemistry Lecture notes, books, related articles, computer
3 Uses of proteins as a biotechnological product Lecture notes, books, related articles, computer
4 Antibodies as a biotechnological product Lecture notes, books, related articles, computer
5 Antibody development Lecture notes, books, related articles, computer
6 Pilot and large-scale production of antibodies Lecture notes, books, related articles, computer
7 Uses of antibody drugs Lecture notes, books, related articles, computer
8 mid-term exam
9 Enzymes and other proteins as biotechnological products Lecture notes, books, related articles, computer
10 Enzyme immobilization and usage areas of enzymes Lecture notes, books, related articles, computer
11 Industrial production of enzymes Lecture notes, books, related articles, computer
12 The use of recombinant DNA technology in protein production. Lecture notes, books, related articles, computer
13 Use of bioreactors in protein production. Lecture notes, books, related articles, computer
14 Biosafety in the production of proteins as biotechnological products. Lecture notes, books, related articles, computer
15 Biotechnology companies and bioentrepreneurship. Lecture notes, books, related articles, computer
16 final exam
Recommend Course Book / Supplementary Book/Reading
1 Thieman & Palladino. 2013. Biyoteknolojiye Giriş. Palme Yayınları.
2 Walsh G. (2001). Proteins: Biochemistry and Biotechnology. Wiley.
Required Course instruments and materials
Lecture notes, books, related articles, computer

Assessment Methods
Type of Assessment Week Hours Weight(%)
mid-term exam 8 40
Other assessment methods
1.Oral Examination
2.Quiz
3.Laboratory exam
4.Presentation
5.Report
6.Workshop
7.Performance Project
8.Term Paper
9.Project
final exam 16 60

Student Work Load
Type of Work Weekly Hours Number of Weeks Work Load
Weekly Course Hours (Theoretical+Practice) 3 14 42
Outside Class
       a) Reading 3 14 42
       b) Search in internet/Library 3 14 42
       c) Performance Project 0
       d) Prepare a workshop/Presentation/Report 0
       e) Term paper/Project 0
Oral Examination 0
Quiz 0
Laboratory exam 0
Own study for mid-term exam 3 7 21
mid-term exam 2 1 2
Own study for final exam 3 7 21
final exam 2 1 2
0
0
Total work load; 172